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學習快評丨qibao666888　　蛋??(dan)白??(bai)質??(zhi)是??(shi)由??(you)20種??(zhong)氨??(an)基??(ji)酸??(suan)組??(zu)成??(cheng)的??(de)一??(yi)條?(tiao)高??(gao)分??(fen)子??(zi)鏈?(lian)??，這??(zhe)個??(ge)高??(gao)分??(fen)子??(zi)鏈??(lian)會?(hui)扭??(niu)曲?(qu)并??(bing)折??(zhe)疊??(die)成??(cheng)獨??(du)特??(te)的??(de)三??(san)維??(wei)結?(jie)構??(gou)??，正??(zheng)是??(shi)這??(zhe)種??(zhong)獨??(du)特??(te)結??(jie)構??(gou)賦??(fu)予??(yu)了??(le)特??(te)定??(ding)蛋??(dan)白??(bai)質??(zhi)的??(de)生??(sheng)物?(wu)功??(gong)能??(neng)??。??要??(yao)設秘(she)計??(ji)出??(chu)一??(yi)款?(kuan)成??(cheng)功??(gong)的??(de)蛋??(dan)白?(bai)質??(zhi)產??(chan)品??(pin)??，不??(bu)能?(neng)只??(zhi)關??(guan)注??(zhu)它??(ta)的??(de)三?(san)維??(wei)結??(jie)構?(gou)??，而??(er)是??(shi)要??(yao)能??(neng)成??(cheng)功??(gong)預??(yu)測?(ce)和??(he)設??(she)計??(ji)它??(ta)的??(de)功??(gong)能??(neng)??。洪??(hong)亮??(liang)團??(tuan)隊??(dui)直?(zhi)接??(jie)瞄??(miao)準??(zhun)“功??(gong)能??(neng)預??(yu)測??(ce)”這??(zhe)一??(yi)終??(zhong)極??(ji)目??(mu)標??(biao)??，將??(jiang)復?(fu)雜??(za)的??(de)蛋??(dan)白??(bai)質??(zhi)設??(she)計??(ji)變?(bian)成??(cheng)以??(yi)需??(xu)求??(qiu)為?(wei)導??(dao)向??(xiang)??，配??(pei)合?(he)少??(shao)量??(liang)實??(shi)驗??(yan)輸??(shu)出??(chu)結??(jie)果??(guo)的??(de)簡??(jian)單??(dan)過??(guo)程??(cheng)???！　　拔??(wo)們??(men)訓??(xun)練??(lian)了??(le)Venus(啟??(qi)明??(ming)星??(xing))系??(xi)列??(lie)模??(mo)型??(xing)??，與??(yu)DeepMind團??(tuan)隊??(dui)的?(de)AlphaFold預??(yu)測??(ce)蛋??(dan)白??(bai)質?(zhi)結??(jie)構??(gou)不??(bu)同??(tong)??，這??(zhe)個??(ge)模??(mo)型??(xing)學??(xue)習??(xi)自??(zi)然??(ran)界??(jie)蛋??(dan)白?(bai)質??(zhi)序??(xu)列??(lie)的??(de)組??(zu)織??(zhi)規(guī)??(gui)則??(ze)以??(yi)及??(ji)它??(ta)與??(yu)功??(gong)能??(neng)之??(zhi)間?(jian)的??(de)關??(guan)系??(xi)??，其??(qi)預?(yu)測?(ce)蛋??(dan)白??(bai)質??(zhi)突??(tu)變??(bian)功??(gong)能??(neng)的??(de)精??(jing)度??(du)位??(wei)居??(ju)行??(xing)業(yè)??(ye)榜?(bang)單??(dan)之??(zhi)首??(shou)??。??”洪??(hong)亮??(liang)說??(shuo)??，Venus系??(xi)列??(lie)模??(mo)型??(xing)具??(ju)備??(bei)兩??(liang)大??(da)核??(he)心?(xin)功??(gong)能?(neng)：“AI定??(ding)向??(xiang)進??(jin)化??(hua)”與??(yu)“AI挖??(wa)酶??(mei)”??。這??(zhe)些??(xie)超?(chao)常??(chang)規(guī)??(gui)功??(gong)能??(neng)的??(de)蛋??(dan)白??(bai)質??(zhi)在??(zai)生??(sheng)物??(wu)技??(ji)術??(shu)、醫(yī)??(yi)藥??(yao)研??(yan)發(fā)??(fa)和??(he)工?(gong)業(yè)??(ye)生??(sheng)產??(chan)中??(zhong)具??(ju)有??(you)巨?(ju)大??(da)的??(de)應?(ying)用??(yong)潛??(qian)力??(li)??，能??(neng)夠??(gou)為??(wei)相??(xiang)關??(guan)領??(ling)域??(yu)帶??(dai)來??(lai)創(chuàng)??(chuang)新??(xin)和??(he)突??(tu)破?(po)??。。