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　　蛋?(dan)白??(bai)質(zhì)??(zhi)是??(shi)由??(you)氨??(an)基??(ji)酸??(suan)序??(xu)列??(lie)構(gòu)??(gou)成??(cheng)的??(de)??，氨??(an)基??(ji)酸??(suan)序??(xu)列??(lie)的??(de)長??(chang)度??(du)從??(cong)數(shù)??(shu)百??(bai)個(gè)??(ge)到??(dao)上??(shang)千??(qian)個(gè)??(ge)不??(bu)等??(deng)?。??AI時(shí)??(shi)代??(dai)??，數(shù)??(shu)據(jù)??(ju)是??(shi)推??(tui)動??(dong)技??(ji)術(shù)??(shu)進(jìn)??(jin)步??(bu)的??(de)核??(he)心??(xin)資??(zi)源??(yuan)??，龐??(pang)大??(da)的??(de)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)數(shù)??(shu)據(jù)??(ju)集??(ji)能??(neng)幫??(bang)助??(zhu)模??(mo)型?(xing)更??(geng)好??(hao)地??(di)理??(li)解??(jie)蛋??(dan)白??(bai)質(zhì)??(zhi)的??(de)序??(xu)列??(lie)、結(jié)??(jie)構(gòu)?(gou)和??(he)功??(gong)能??(neng)關(guān)??(guan)系??(xi)?。洪??(hong)亮??(liang)團(tuán)?(tuan)隊(duì)??(dui)建??(jian)立??(li)的??(de)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)數(shù)??(shu)據(jù)??(ju)集??(ji)Venus-Pod(Venus-Protein Outsize Dataset)含??(han)有??(you)近??(jin)90億??(yi)條??(tiao)蛋??(dan)白?(bai)質(zhì)?(zhi)序??(xu)列??(lie)??，包?(bao)含?(han)數(shù)??(shu)億??(yi)個(gè)?(ge)功??(gong)能??(neng)標(biāo)??(biao)簽??(qian)??，是??(shi)全??(quan)球??(qiu)數(shù)??(shu)據(jù)??(ju)規(guī)??(gui)模??(mo)最??(zui)大??(da)、功??(gong)能??(neng)批??(pi)注??(zhu)標(biāo)??(biao)簽??(qian)最??(zui)多祝(duo)的??(de)數(shù)?(shu)據(jù)??(ju)集??(ji)??，也??(ye)是??(shi)另?(ling)一??(yi)行??(xing)業(yè)??(ye)知??(zhi)名?(ming)模??(mo)型??(xing)——美??(mei)國??(guo)ESM-C模??(mo)型?(xing)訓(xùn)??(xun)練??(lian)用?(yong)的??(de)21億??(yi)蛋??(dan)白??(bai)質(zhì)?(zhi)序??(xu)列?(lie)的??(de)4倍??(bei)體??(ti)量??(liang)??！　　拔??(wo)們??(men)訓(xùn)??(xun)練??(lian)了??(le)Venus(啟?(qi)明??(ming)星??(xing))系??(xi)列??(lie)模??(mo)型??(xing)??，與??(yu)DeepMind團(tuán)?(tuan)隊(duì)??(dui)的??(de)AlphaFold預(yù)??(yu)測??(ce)蛋??(dan)白??(bai)質(zhì)??(zhi)結(jié)??(jie)構(gòu)??(gou)不??(bu)同??(tong)??，這??(zhe)個(gè)??(ge)模??(mo)型??(xing)學(xué)??(xue)習(xí)?(xi)自??(zi)然?(ran)界??(jie)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)的??(de)組??(zu)織??(zhi)規(guī)??(gui)則??(ze)以??(yi)及?(ji)它??(ta)與??(yu)功??(gong)能??(neng)之??(zhi)間??(jian)的??(de)關(guān)??(guan)系??(xi)??，其??(qi)預(yù)??(yu)測??(ce)蛋??(dan)白??(bai)質(zhì)??(zhi)突??(tu)變??(bian)功??(gong)能?(neng)的??(de)精??(jing)度??(du)位?(wei)居?(ju)行??(xing)業(yè)??(ye)榜??(bang)單??(dan)之??(zhi)首??(shou)?。??”洪??(hong)亮??(liang)說??(shuo)??，Venus系??(xi)列??(lie)模??(mo)型??(xing)具??(ju)備??(bei)兩??(liang)大??(da)核?(he)心??(xin)功??(gong)能??(neng)：“AI定??(ding)向??(xiang)進(jìn)??(jin)化??(hua)”與??(yu)“AI挖??(wa)酶??(mei)”?。這??(zhe)些??(xie)超??(chao)常?(chang)規(guī)??(gui)功??(gong)能??(neng)的??(de)蛋??(dan)白??(bai)質(zhì)??(zhi)在??(zai)生??(sheng)物??(wu)技??(ji)術(shù)??(shu)、醫(yī)??(yi)藥??(yao)研??(yan)發(fā)??(fa)和??(he)工??(gong)業(yè)??(ye)生??(sheng)產(chǎn)??(chan)中??(zhong)具??(ju)有??(you)巨??(ju)大??(da)的??(de)應(yīng)??(ying)用??(yong)潛??(qian)力?(li)??，能??(neng)夠?(gou)為??(wei)相??(xiang)關(guān)??(guan)領(lǐng)??(ling)域??(yu)帶??(dai)來??(lai)創(chuàng)??(chuang)新??(xin)和??(he)突??(tu)破?(po)?。。