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原標(biāo)題：日本理论片午夜在线观看

學(xué)習(xí)快評(píng)丨qibao666888　　這??(zhe)個(gè)??(ge)比??(bi)喻??(yu)的??(de)背??(bei)后??(hou)是??(shi)雙??(shuang)重??(zhong)突??(tu)破??(po)：理??(li)論??(lun)上??(shang)首??(shou)次??(ci)證??(zheng)明??(ming)細(xì)??(xi)胞??(bao)周??(zhou)期??(qi)調(diào)??(tiao)控??(kong)蛋?(dan)白??(bai)能??(neng)指??(zhi)揮??(hui)非??(fei)分??(fen)裂??(lie)細(xì)??(xi)胞??(bao)的??(de)炎??(yan)癥??(zheng)反??(fan)應(yīng)??(ying)?，臨??(lin)床??(chuang)上??(shang)開(kāi)??(kai)辟??(pi)了??(le)“一??(yi)藥??(yao)多??(duo)治?(zhi)”的??(de)可??(ke)能??(neng)性??(xing)??。??丁??(ding)勝??(sheng)表??(biao)示??(shi)?，這??(zhe)一??(yi)研??(yan)究??(jiu)不??(bu)僅??(jin)深??(shen)化??(hua)了??(le)人??(ren)們??(men)對(duì)??(dui)小??(xiao)膠??(jiao)質(zhì)??(zhi)細(xì)??(xi)胞??(bao)免??(mian)疫??(yi)調(diào)??(tiao)控??(kong)機(jī)??(ji)制??(zhi)的?(de)理??(li)解??(jie)?，也??(ye)為??(wei)未??(wei)來(lái)??(lai)開(kāi)?(kai)發(fā)??(fa)神??(shen)經(jīng)??(jing)炎??(yan)癥??(zheng)相??(xiang)關(guān)??(guan)疾??(ji)病??(bing)的??(de)精??(jing)準(zhǔn)??(zhun)治??(zhi)療??(liao)策??(ce)略?(lve)提??(ti)供??(gong)了??(le)科??(ke)學(xué)??(xue)依??(yi)據(jù)??(ju)??。　　研??(yan)究??(jiu)團(tuán)?(tuan)隊(duì)??(dui)通??(tong)過(guò)??(guo)基??(ji)因?(yin)編??(bian)輯??(ji)技??(ji)術(shù)??(shu)??，在??(zai)實(shí)??(shi)驗(yàn)??(yan)室??(shi)培??(pei)養(yǎng)??(yang)的??(de)人??(ren)源??(yuan)小??(xiao)膠??(jiao)質(zhì)??(zhi)細(xì)?(xi)胞??(bao)中??(zhong)敲??(qiao)除??(chu)MEF2C基??(ji)因??(yin)??。??失??(shi)去??(qu)這??(zhe)個(gè)??(ge)“車(chē)??(che)速??(su)控??(kong)制??(zhi)系??(xi)統(tǒng)?(tong)核??(he)心??(xin)元??(yuan)件??(jian)”的??(de)細(xì)??(xi)胞??(bao)隨??(sui)之??(zhi)陷??(xian)入??(ru)混??(hun)亂??(luan)??，負(fù)??(fu)責(zé)?(ze)抑?(yi)制??(zhi)過(guò)??(guo)度??(du)反??(fan)應(yīng)??(ying)的??(de)p21蛋??(dan)白??(bai)產(chǎn)??(chan)量??(liang)銳??(rui)減??(jian)??，而??(er)本??(ben)該??(gai)被??(bei)約??(yue)束??(shu)的?(de)CDK2激??(ji)酶?(mei)卻??(que)異??(yi)常??(chang)活??(huo)躍??(yue)??，這??(zhe)就??(jiu)好??(hao)比??(bi)控??(kong)速??(su)系??(xi)統(tǒng)??(tong)的?(de)關(guān)??(guan)鍵??(jian)制??(zhi)動(dòng)??(dong)環(huán)??(huan)節(jié)??(jie)失??(shi)效?(xiao)??。更??(geng)糟??(zao)的??(de)是??(shi)??，CDK2的??(de)過(guò)??(guo)度??(du)活??(huo)躍??(yue)直??(zhi)接??(jie)摧??(cui)毀??(hui)了??(le)RB蛋??(dan)白??(bai)??。這??(zhe)個(gè)??(ge)如??(ru)同??(tong)汽??(qi)車(chē)??(che)“安??(an)全??(quan)鎖??(suo)”的??(de)關(guān)??(guan)鍵??(jian)分??(fen)子??(zi)一??(yi)旦??(dan)缺??(que)失??(shi)??，就?(jiu)會(huì)??(hui)在??(zai)小??(xiao)膠??(jiao)質(zhì)??(zhi)細(xì)??(xi)胞??(bao)被??(bei)激??(ji)活?(huo)時(shí)??(shi)徹??(che)底??(di)釋??(shi)放??(fang)NF-κB信??(xin)號(hào)??(hao)通??(tong)路??(lu)??，繼??(ji)而??(er)引??(yin)發(fā)??(fa)TNF-α、IL-6等??(deng)炎??(yan)癥??(zheng)因??(yin)子??(zi)的??(de)大??(da)規(guī)??(gui)模??(mo)爆??(bao)發(fā)??(fa)??，如??(ru)同??(tong)自??(zi)動(dòng)??(dong)駕??(jia)駛?(shi)汽??(qi)車(chē)??(che)在??(zai)速??(su)控?(kong)系??(xi)統(tǒng)??(tong)失??(shi)靈??(ling)時(shí)??(shi)進(jìn)??(jin)行??(xing)加??(jia)速??(su)??，會(huì)??(hui)橫??(heng)沖??(chong)直??(zhi)撞??(zhuang)造??(zao)成??(cheng)嚴(yán)??(yan)重??(zhong)破??(po)壞??(huai)??。。