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　　蛋??(dan)白??(bai)質(zhì)??(zhi)是??(shi)由??(you)氨??(an)基??(ji)酸??(suan)序??(xu)列??(lie)構(gòu)??(gou)成??(cheng)的??(de)??，氨??(an)基??(ji)酸??(suan)序??(xu)列??(lie)的??(de)長??(chang)度??(du)從??(cong)數(shù)??(shu)百??(bai)個(gè)??(ge)到??(dao)上??(shang)千??(qian)個(gè)??(ge)不??(bu)等??(deng)??。??AI時(shí)??(shi)代??(dai)??，數(shù)??(shu)據(jù)??(ju)是??(shi)推?(tui)動(dòng)??(dong)技??(ji)術(shù)?(shu)進(jìn)??(jin)步??(bu)的?(de)核??(he)心??(xin)資??(zi)源??(yuan)??，龐??(pang)大??(da)的??(de)蛋??(dan)白??(bai)質(zhì)?(zhi)序??(xu)列??(lie)數(shù)??(shu)據(jù)??(ju)集??(ji)能??(neng)幫??(bang)助??(zhu)模??(mo)型??(xing)更??(geng)好??(hao)地?(di)理??(li)解?(jie)蛋??(dan)白??(bai)質(zhì)??(zhi)的??(de)序?(xu)列?(lie)、結(jié)??(jie)構(gòu)??(gou)和??(he)功??(gong)能??(neng)關(guān)?(guan)系??(xi)??。洪??(hong)亮??(liang)團(tuán)??(tuan)隊(duì)??(dui)建??(jian)立??(li)的??(de)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)數(shù)??(shu)據(jù)??(ju)集??(ji)Venus-Pod(Venus-Protein Outsize Dataset)含??(han)有??(you)近??(jin)90億??(yi)條??(tiao)蛋??(dan)白??(bai)質(zhì)?(zhi)序??(xu)列??(lie)??，包?(bao)含??(han)數(shù)??(shu)億??(yi)個(gè)??(ge)功??(gong)能??(neng)標(biāo)??(biao)簽??(qian)??，是??(shi)全??(quan)球??(qiu)數(shù)??(shu)據(jù)??(ju)規(guī)??(gui)模??(mo)最??(zui)大??(da)、功??(gong)能??(neng)批??(pi)注??(zhu)標(biāo)??(biao)簽??(qian)最??(zui)多??(duo)的??(de)數(shù)??(shu)據(jù)??(ju)集??(ji)??，也??(ye)是??(shi)另??(ling)一??(yi)行??(xing)業(yè)??(ye)知??(zhi)名??(ming)模??(mo)型??(xing)——美??(mei)國??(guo)ESM-C模??(mo)型??(xing)訓(xùn)??(xun)練??(lian)用??(yong)的??(de)21億??(yi)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)的??(de)4倍??(bei)體??(ti)量??(liang)??。　　“我?(wo)們??(men)訓(xùn)??(xun)練??(lian)了??(le)Venus(啟??(qi)明??(ming)星??(xing))系??(xi)列?(lie)模??(mo)型??(xing)??，與??(yu)DeepMind團(tuán)??(tuan)隊(duì)?(dui)的??(de)AlphaFold預(yù)??(yu)測??(ce)蛋??(dan)白?(bai)質(zhì)??(zhi)結(jié)??(jie)構(gòu)??(gou)不??(bu)同??(tong)??，這??(zhe)個(gè)??(ge)模??(mo)型??(xing)學(xué)??(xue)習(xí)??(xi)自??(zi)然??(ran)界??(jie)蛋??(dan)白??(bai)質(zhì)??(zhi)序??(xu)列??(lie)的?(de)組??(zu)織??(zhi)規(guī)??(gui)則??(ze)以??(yi)及??(ji)它??(ta)與??(yu)功??(gong)能?(neng)之??(zhi)間??(jian)的??(de)關(guān)?(guan)系??(xi)??，其??(qi)預(yù)??(yu)測??(ce)蛋?(dan)白祝(bai)質(zhì)??(zhi)突??(tu)變??(bian)功??(gong)能??(neng)的??(de)精?(jing)度??(du)位??(wei)居??(ju)行??(xing)業(yè)??(ye)榜??(bang)單??(dan)之??(zhi)首??(shou)?。??”洪??(hong)亮??(liang)說??(shuo)??，Venus系??(xi)列??(lie)模?(mo)型??(xing)具??(ju)備??(bei)兩??(liang)大??(da)核??(he)心??(xin)功??(gong)能??(neng)：“AI定??(ding)向??(xiang)進(jìn)??(jin)化??(hua)”與??(yu)“AI挖??(wa)酶??(mei)”?。這??(zhe)些??(xie)超??(chao)常??(chang)規(guī)??(gui)功??(gong)能??(neng)的??(de)蛋??(dan)白??(bai)質(zhì)??(zhi)在??(zai)生??(sheng)物??(wu)技??(ji)術(shù)?(shu)、醫(yī)??(yi)藥??(yao)研??(yan)發(fā)?(fa)和??(he)工??(gong)業(yè)??(ye)生??(sheng)產(chǎn)??(chan)中??(zhong)具秘(ju)有??(you)巨??(ju)大??(da)的??(de)應(yīng)??(ying)用??(yong)潛??(qian)力??(li)??，能??(neng)夠??(gou)為??(wei)相??(xiang)關(guān)??(guan)領(lǐng)?(ling)域??(yu)帶??(dai)來??(lai)創(chuàng)??(chuang)新?(xin)和??(he)突??(tu)破??(po)?。YPRITXSVHTqibao666888　　dan ??(dan)bai ??(bai)zhi ??(zhi)shi ??(shi)you ??(you)an ??(an)ji ??(ji)suan ??(suan)xu ??(xu)lie ??(lie)gou ??(gou)cheng ??(cheng)de ??(de)??，an ??(an)ji ??(ji)suan ??(suan)xu ??(xu)lie ??(lie)de ??(de)chang ??(chang)du ??(du)cong ??(cong)shu ??(shu)bai ??(bai)ge ??(ge)dao ??(dao)shang ??(shang)qian ??(qian)ge ??(ge)bu ??(bu)deng ??(deng)??。??AIshi ??(shi)dai ??(dai)??，shu ??(shu)ju ??(ju)shi ??(shi)tui ?(tui)dong ??(dong)ji ??(ji)shu ?(shu)jin ??(jin)bu ??(bu)de ?(de)he ??(he)xin ??(xin)zi ??(zi)yuan ??(yuan)??，pang ??(pang)da ??(da)de ??(de)dan ??(dan)bai ??(bai)zhi ?(zhi)xu ??(xu)lie ??(lie)shu ??(shu)ju ??(ju)ji ??(ji)neng ??(neng)bang ??(bang)zhu ??(zhu)mo ??(mo)xing ??(xing)geng ??(geng)hao ??(hao)di ?(di)li ??(li)jie ?(jie)dan ??(dan)bai ??(bai)zhi ??(zhi)de ??(de)xu ?(xu)lie ?(lie)、jie ??(jie)gou ??(gou)he ??(he)gong ??(gong)neng ??(neng)guan ?(guan)xi ??(xi)??。hong ??(hong)liang ??(liang)tuan ??(tuan)dui ??(dui)jian ??(jian)li ??(li)de ??(de)dan ??(dan)bai ??(bai)zhi ??(zhi)xu ??(xu)lie ??(lie)shu ??(shu)ju ??(ju)ji ??(ji)Venus-Pod(Venus-Protein Outsize Dataset)han ??(han)you ??(you)jin ??(jin)90yi ??(yi)tiao ??(tiao)dan ??(dan)bai ??(bai)zhi ?(zhi)xu ??(xu)lie ??(lie)??，bao ?(bao)han ??(han)shu ??(shu)yi ??(yi)ge ??(ge)gong ??(gong)neng ??(neng)biao ??(biao)qian ??(qian)??，shi ??(shi)quan ??(quan)qiu ??(qiu)shu ??(shu)ju ??(ju)gui ??(gui)mo ??(mo)zui ??(zui)da ??(da)、gong ??(gong)neng ??(neng)pi ??(pi)zhu ??(zhu)biao ??(biao)qian ??(qian)zui ??(zui)duo ??(duo)de ??(de)shu ??(shu)ju ??(ju)ji ??(ji)??，ye ??(ye)shi ??(shi)ling ??(ling)yi ??(yi)xing ??(xing)ye ??(ye)zhi ??(zhi)ming ??(ming)mo ??(mo)xing ??(xing)——mei ??(mei)guo ??(guo)ESM-Cmo ??(mo)xing ??(xing)xun ??(xun)lian ??(lian)yong ??(yong)de ??(de)21yi ??(yi)dan ??(dan)bai ??(bai)zhi ??(zhi)xu ??(xu)lie ??(lie)de ??(de)4bei ??(bei)ti ??(ti)liang ??(liang)???！　　皐o ?(wo)men ??(men)xun ??(xun)lian ??(lian)le ??(le)Venus(qi ??(qi)ming ??(ming)xing ??(xing))xi ??(xi)lie ?(lie)mo ??(mo)xing ??(xing)??，yu ??(yu)DeepMindtuan ??(tuan)dui ?(dui)de ??(de)AlphaFoldyu ??(yu)ce ??(ce)dan ??(dan)bai ?(bai)zhi ??(zhi)jie ??(jie)gou ??(gou)bu ??(bu)tong ??(tong)??，zhe ??(zhe)ge ??(ge)mo ??(mo)xing ??(xing)xue ??(xue)xi ??(xi)zi ??(zi)ran ??(ran)jie ??(jie)dan ??(dan)bai ??(bai)zhi ??(zhi)xu ??(xu)lie ??(lie)de ?(de)zu ??(zu)zhi ??(zhi)gui ??(gui)ze ??(ze)yi ??(yi)ji ??(ji)ta ??(ta)yu ??(yu)gong ??(gong)neng ?(neng)zhi ??(zhi)jian ??(jian)de ??(de)guan ?(guan)xi ??(xi)??，qi ??(qi)yu ??(yu)ce ??(ce)dan ?(dan)bai 祝(bai)zhi ??(zhi)tu ??(tu)bian ??(bian)gong ??(gong)neng ??(neng)de ??(de)jing ?(jing)du ??(du)wei ??(wei)ju ??(ju)xing ??(xing)ye ??(ye)bang ??(bang)dan ??(dan)zhi ??(zhi)shou ??(shou)?。??”hong ??(hong)liang ??(liang)shuo ??(shuo)??，Venusxi ??(xi)lie ??(lie)mo ?(mo)xing ??(xing)ju ??(ju)bei ??(bei)liang ??(liang)da ??(da)he ??(he)xin ??(xin)gong ??(gong)neng ??(neng)：“AIding ??(ding)xiang ??(xiang)jin ??(jin)hua ??(hua)”yu ??(yu)“AIwa ??(wa)mei ??(mei)”?。zhe ??(zhe)xie ??(xie)chao ??(chao)chang ??(chang)gui ??(gui)gong ??(gong)neng ??(neng)de ??(de)dan ??(dan)bai ??(bai)zhi ??(zhi)zai ??(zai)sheng ??(sheng)wu ??(wu)ji ??(ji)shu ?(shu)、yi ??(yi)yao ??(yao)yan ??(yan)fa ?(fa)he ??(he)gong ??(gong)ye ??(ye)sheng ??(sheng)chan ??(chan)zhong ??(zhong)ju 秘(ju)you ??(you)ju ??(ju)da ??(da)de ??(de)ying ??(ying)yong ??(yong)qian ??(qian)li ??(li)??，neng ??(neng)gou ??(gou)wei ??(wei)xiang ??(xiang)guan ??(guan)ling ?(ling)yu ??(yu)dai ??(dai)lai ??(lai)chuang ??(chuang)xin ?(xin)he ??(he)tu ??(tu)po ??(po)?。